… of PAMPs and trigger the release of pro-inflammatory cytokines. … that cigarette smoke extract
can directly upregulate … MRC5, human lung fibroblasts cell line, exposed to cigarette smoke. …

… -1β downregulated the gene and protein expression levels of … -κB and various pro-inflammatory
cytokines are involved in … In the present study, the role of the pro-inflammatory cytokine …

… cigarette smoke condensate (CSC) induces the production of … -8 secretion in fibroblast-like
synoviocytes from RA patients by … production of proinflammatory cytokines from synoviocytes …

… and subsequent proinflammatory cytokine production by cigarette … fibroblast-like synoviocytes
with SV40 T antigen gene [22]. … any significant upregulation of AhR expression by TNFα …

… inflammation in the human lung fibroblast cell line HFL1. The … stimulate the expression of
apoptosis-specific genes through … been reported to upregulate DUSP16 expression and inhibit …

… of large amounts of pro-inflammatory cytokines, chemokines, … In line with our RNAseq results,
silencing of BRD3 induced … ], and increases oxidative stress in fibroblasts [48]. Among BET …

… , smoke, by provoking oxidative stress, may contribute to lupus disease by dysregulating DNA
demethylation, upregulating immune genes, … Not only cigarette smoke but also air pollution …

… that cigarette smoke induces the synthesis of Hsp70 protein in … Dotted line represents
expression of mRNA in non-treated … CSE influence pro-inflammatory cytokine production and alter …

… expression of MMP1, 3 and 15 in fibroblast-like synoviocytes. … Therefore, inhibiting pro-inflammatory
cytokines or … In RA patients, upregulation of miR-146a causes persistent production …

… were measured in RA human fibroblast-like synoviocytes (… is activated by pro-inflammatory
cytokines that facilitate the … As expected, the TNF-α treatment promoted the upregulation of NF-…